Brand description and names
Drug information provided by:IBM Micromedex
- Artadent Dental with Epinephrine
- Strong Ultacan
The combined injection of articaine and epinephrine is used to numb the mouth before a dental procedure.
This medication must be administered by or under the direct supervision of your dentist.
This product is available in the following dosage forms:
When deciding to use a drug, the risks of taking it must be weighed against the good it will do. This is a decision for you and your doctor to make. For this drug, the following should be considered:
Tell your doctor if you have ever had an allergic or unusual reaction to this medicine or any other medicine. Also tell your healthcare professional if you have any other allergies, such as food, dyes, preservatives or animals. For over-the-counter products, read the label or packaging ingredients carefully.
Appropriate studies of the relationship of age to the effects of combined injection of articaine and epinephrine in children less than 4 years of age have not been performed. Safety and efficacy have not been established.
Appropriate studies to date have not demonstrated specific geriatric issues that would limit the usefulness of combined articaine and epinephrine injection in the elderly. However, elderly patients are more sensitive to the effects of this medication than younger adults.
There are no adequate studies in women to determine the infant risk of using this medication while breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
While certain drugs should not be used together, in other cases, two different drugs can be used together even if an interaction occurs. In these cases your doctor may want to change the dose or other precautions may be necessary. When you are receiving this medication, it is especially important that your healthcare professional knows if you are taking any of the medications listed below. The following interactions have been selected based on their potential importance and are not necessarily exhaustive.
The use of this medication with any of the following medications is not recommended. Your doctor may decide not to treat you with this medicine or change some of the other medicines you take.
The use of this medication with any of the following medications is generally not recommended, but may be necessary in some cases. If both drugs are prescribed together, your doctor may change the dose or how often you use one or both drugs.
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Using this medication with any of the following medications may increase your risk of certain side effects, but using both medications may be the best treatment for you. If both drugs are prescribed together, your doctor may change the dose or how often you use one or both drugs.
Certain medications should not be used at or near the time of eating food or certain types of food, as interactions may occur. The use of alcohol or tobacco with certain medications can also cause interactions. Talk to your healthcare professional about using medications with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of this medication. Be sure to let your doctor know if you have any other medical issues, especially:
- asthma o
- blood vessel disease or
- heart disease or
- Heart rhythm problems (e.g. heart block): Use with caution. It may increase the risk of further side effects.
- Glucose-6-phosphate dehydrogenase deficiency (G6PD) or
- heart problems or
- Lung or Breathing Problems – Use with caution. May increase the risk of methemoglobinemia.
- kidney disease or
- Liver disease, severe - Use with caution. The effects may be enhanced due to the slower elimination of the drug from the body.
- Methemoglobinemia (blood disorder), hereditary or idiopathic (unknown cause) or
- Sulphite Allergy: Should not be used in patients with these conditions.
Your dentist or other trained healthcare professional will give you this medication in a medical facility. It is given through a needle that is placed into the gum, usually near the bottom of the tongue. Before receiving the injection, an anesthetic gel may be rubbed into the gum to make the injection more comfortable.
This medication should only cause numbness in the area where it is injected. You may experience a temporary loss of feeling or movement in the injected area. This type of numbing procedure is called local anesthesia. It is not intended to make you fall asleep or pass out.
Your mouth may feel numb for several hours. To avoid injury after dental work, do not eat or drink until normal sensation has returned to the area. Do not test mouthfeel by biting or pricking the treated area.
It is very important that your dentist closely monitor your child's progress while receiving this medication to see that it is working properly. Blood tests may be needed to check for unwanted effects.
This medicine may increase your risk of serious heart and blood vessel problems, such as a heart attack, heart rhythm changes, or low blood pressure. See your doctor if you experience chest pain or discomfort, pain or discomfort in your arms, jaw, back, or neck, dizziness, fainting, rapid heartbeat, rapid heartbeat, trouble breathing, or unusual tiredness or weakness.
Tell your dentist right away if you experience the following symptoms with this medication: anxiety, blurred vision, depression, drowsiness, dizziness, nausea or vomiting, numbness and tingling in your mouth or lips, restlessness, ringing in your ears, slurred speech, or tremors
This medicine can cause a rare but serious blood problem called methemoglobinemia. The risk may be increased in children younger than 6 months of age, elderly patients, or patients with certain birth defects. It is more likely to occur in patients who receive a lot of medication, but it can also occur with small amounts. Talk to your doctor right away if you or your child have the following symptoms after receiving this medication: pale, gray, or bluish skin, lips, or nails, confusion, headache, dizziness, rapid heartbeat, or unusual tiredness or weakness.
This medication can cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Contact your doctor immediately if you experience a rash, itching, hoarseness, difficulty breathing, difficulty swallowing, or swelling of your hands, face, mouth, or throat after receiving this medication.
Do not take other medicines unless you have discussed them with your doctor. This includes prescription or over-the-counter (OTC) drugs and herbal or vitamin supplements.
Along with its necessary effects, a drug can cause some unwanted effects. While not all of these side effects may occur, if they do, they may require medical attention.
Talk to your doctor or nurse straight away if you experience any of the following side effects:
- Bleeding, redness or swelling of the gums
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- fast, irregular, pounding, or pounding pulse or heartbeat
- lower back or side pain
- mouth ulcers
- painful or difficult urination
- swelling of the face
- swelling or irritation of the mouth
- Blurred vision
- body aches or pain
- coughing up blood
- difficulty breathing or swallowing
- difficulty opening the mouth
- dry throat or sore throat
- facial paralysis
- headache, intense and throbbing
- increased bone pain
- increased menstrual flow or vaginal bleeding
- increased sensitivity to pain or touch
- large, flat, blue or purple spots on the skin
- muscle spasm, especially of the neck and back
- banging in the ears
- prolonged bleeding from cuts
- red or black stools, tar
- dark red or brown urine
- redness or swelling in the ear
- runny or congested nose
- slow or fast heartbeat
- tongue swelling
- swollen, painful, or tender lymph nodes in the neck, armpit, or groin
- tingling in hands and feet
- difficulty swallowing
- voice changes
- Larger, dilated, or enlarged pupils (black part of the eye)
- burning, tingling, itching, numbness, prickling, tingling, or tingling in the mouth
- chest pain or discomfort
- double vision
- drooping upper eyelids
- increased sensitivity of the eyes to light
- pain in the shoulders, arms, jaw, or neck
- double selling
There may be some side effects that usually do not require medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your healthcare professional can tell you about ways to prevent or reduce some of these side effects. Check with your healthcare professional if any of the following side effects continue or are bothersome, or if you have any questions about them:
- change of taste
- unusual or unpleasant bad taste (after)
- movement difficulty
- dry mouth
- increased salivation
- itchy skin
- joint pain or swelling
- lack or loss of strength
- muscle pain or stiffness
- pain or burning at the injection site
- runny nose
- drowsiness or unusual drowsiness
- to sneeze
- stomach pain, discomfort or pain
Other side effects not listed may also occur in some patients. If you notice any other effects, consult your healthcare professional.
Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.
Parts of this document were last updated: November 1, 2022
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